After the lone Doom Marine repelled Hell's earlier invasions, the abandoned and heavily irradiated research installations of the Union Aerospace Corporation are placed under quarantine. Years later, a faint satellite signal reveals that a single powerful entity survived the radiation and has begun resurrecting the demonic horde, reanimating the dead into fresh monsters. As the only soldier who has faced and survived Hell before, the Marine is sent in alone to descend into the overrun facilities and the infernal realm beyond, hunting down the demons and the malevolent force reviving them.

Fight against demons in your crusade to hunt down the Mother of Demons and stop Hell's invasion. As the player battle through more than 30 action-packed levels, they have to be on the lookout for enhanced weapons and secrets to help them put an end to the demonic threat.