Metal Gear Solid 3: Snake Eater

At the height of the Cold War, America's greatest agent known as The Boss defects to the Soviet Union. At the same time, an extremist named Colonel Volgin fires an American-made portable nuclear missile at the Soviet design bureau OKB-754, sparking an international incident. In order for America to clear its name and avoid World War III, a man named John and codenamed Naked Snake is dispatched by the special forces unit FOX to assassinate the woman who taught him everything.